Labdane is a natural bicyclic diterpene. It forms the structural core for a wide variety of natural products collectively known as labdanes or labdane diterpenes. The labdanes were so named because the first members of the class were originally obtained from labdanum, a resin derived from the gum rockrose.

A variety of biological activities have been determined for labdane diterpenes including antibacterial, antifungal, antiprotozoal, and anti-inflammatory activities.

Example labdane derivatives

  • Forskolin
  • Galanolactone
  • Isocupressic acid - is an abortifacient component of Cupressus macrocarpa.
  • Medigenin
  • Sclareol
  • Stemodene

See also

  • Abietane

References


Production of distinct diterpenoids using a novel cryptic

Clerodane and diterpenoid glycosides tested for their

diterpenes. A, Basic labdane skeleton. B, Manoyl oxide and

Labdane Alchetron, The Free Social Encyclopedia

Structure of labdane and labdanerelated bicyclic diterpenoids with